Vaginal (vaj-in-al) cancer is more commonly diagnosed in women between the ages of 50 and 70 years old, and in those women whose mother's took the drug, DES, while they were pregnant. The signs and symptoms of vaginal cancer aren't typically apparent until the cancer has advanced. Vaginal discharge often tinged with blood is the most frequent symptom. Irregular spotting and postmenopausal bleeding are common signs. Symptoms associated with the urinary tract, such as burning during urination, frequency, and urgency, are common in vaginal cancer. This occurs because cancers of the lowermost vagina are close to the bladder base and its outlet. Unfortunately, the elasticity of the vagina allows cancers to become rather large before they are detected. Routine pelvic examinations are highly recommended, even if you aren't sexually active. For more information on vaginal cancer, contact your healthcare provider.